CSDB glycosyltransferase search

2 glycosyltransferase activities have been found.
Please note that CSDB GT database covers only a few species: Arabidopsis thaliana, Escherichia coli, Saccharomyces cerevisiae, Acinetobacter baumannii.

Enzyme / Gene Activity Object References
Enzyme name: csh1p
UniProt ID: P38287*
CAZy family: GT32

Gene name: CSH1
Gene GenBank ID: 852458*
Synthesized dimer: DManp(1-2)INO


Donor (ID 34509): ?DManp(1-P-P-5)xXnucG

Acceptor (ID 34606): l?2HOCrt(1-2)[INO(1-P-1)]xXphSphC18

Status: semi-direct evidence in vivo
Confirmation methods: in silico; in vitro (membrane preparation); double mutation; supplementation
ID: 1
Notes: Unlike Dcsg1 cells, the Dcsh1 mutant produced IPC-C (or IPC-D) and mannosylated IPC
species at ratios similar to those in wild-type cells. In the Dcsg1Dcsh1 double
mutant, however, production of MIPC and M(IP)2C was completely abolished
Organism (ID 10157,10896,10898,16655,16656,16657,16658,16659): Saccharomyces cerevisiae SEY6210, KA31-1A, SUY41, EHY227, KHY195, SUY45, SUY49, SUY53

Full structure (ID 34607):

CSDB ID(s): 43539, 45004, 45512

Molecule role (precursor of): glycolipid

Lisman et al. 2004
DOI: 10.1074/jbc.M306119200

Uemura et al. 2003
DOI: 10.1074/jbc.M305498200

Beeler et al. 1997
DOI: 10.1007/s004380050530

Tanaka et al. 2018
DOI: 10.1111/febs.14509

Morimoto et al. 2015
DOI: 10.1111/mmi.12896
Enzyme name: sur1p
UniProt ID: P33300*
CAZy family: GT32

Gene name: SUR1/CSG1/BCL21
Gene GenBank ID: 856050*
Synthesized dimer: DManp(1-2)INO


Donor (ID 34509): ?DManp(1-P-P-5)xXnucG

Acceptor (ID 34606): l?2HOCrt(1-2)[INO(1-P-1)]xXphSphC18

Status: indirect evidence in vivo
Confirmation methods: mutation
ID: 3
Notes: SUR1/CSG1 is both genetically and biochemically related to CSG2. The csg1 mutant
produced greatly reduced levels of the mannosylated sphingolipids MIPC and M(IP)2C,
and accumulated IPC-C and IPC-D; note that IPC-C contains a monohydroxylated
C26 fatty acid whereas the C26 fatty acid in IPC-D is dihydroxylated.
Organism (ID 16660,16661): Saccharomyces cerevisiae DBY689, CuH3

Full structure (ID 34607):

CSDB ID(s): 43539, 45004, 45512

Molecule role (precursor of): glycolipid

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