CSDB glycosyltransferase search

6 glycosyltransferase activities have been found.
Please note that CSDB GT database covers only a few species: Arabidopsis thaliana, Escherichia coli, Saccharomyces cerevisiae, Acinetobacter baumannii.

Enzyme / Gene Activity Object References
Enzyme name: WbnH
UniProt ID: P0DMP6*
CAZy family: GT4

Gene name: wbnH / wbwH / wcmA
Synthesized dimer: aDGalpN(1-3)aDGalpN


Donor (ID 34385): Ac(1-2)?DGalpN(1-P-P-5)xXnucU

Acceptor (ID 34365): Ac(1-2)aDGalpN(1-P-P-1)[Ph(1-11)]Subst // Subst = undecan-1,11-diol

Status: evidence in vitro
Confirmation methods: in vitro (purified protein)
ID: 2086
Organism (ID 2515): Escherichia coli O86:H2

Full structure (ID 34386):

Molecule role (analog of): O-antigen

Yi et al. 2006a
DOI: 10.1016/j.bbrc.2006.03.181
Synthesized dimer: aDGalpN(1-3)aDGalpN


Donor (ID 34385): Ac(1-2)?DGalpN(1-P-P-5)xXnucU

Acceptor (ID 34387): Ac(1-2)aDGalpN(1-P-P-1)Und

Status: evidence in vitro
Confirmation methods: in vitro (purified protein)
ID: 2087
Organism (ID 2515): Escherichia coli O86:H2

Full structure (ID 34388):

Molecule role (analog of): O-antigen

Synthesized dimer: aDGalpN(1-3)aDGalpN


Donor (ID 34385): Ac(1-2)?DGalpN(1-P-P-5)xXnucU

Acceptor (ID 34389): Ac(1-2)aDGalpN(1-P-P-1)Subst // Subst = 3,7,11,15,19,23,27,31,35,39,43-undecamethyl-tetratetraconta-2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E,42-undecaen-1-ol

Status: evidence in vitro
Confirmation methods: in vitro (purified protein)
ID: 2089
Organism (ID 2487): Escherichia coli O86

Exact full structure is unknown

Molecule role (analog of): O-antigen

Woodward et al. 2010
DOI: 10.1038/nchembio.351
Enzyme name: WbiN
Group: WbwH
UniProt ID: A0A0A8J8F1

Gene name: AKG99_13150
Gene cluster ID: AB812039
Synthesized dimer: aDGalpN(1-3)aDGalpN


Status: predicted in silico
Confirmation methods: in silico
ID: 2832
Organism (ID 582): Escherichia coli O127

Full structure (ID 987):

CSDB ID(s): 117352, 108675, 28397, 25395, 20680, 10220

Molecule role: O-antigen

Pettit et al. 2010
DOI: 10.1016/j.bbrc.2010.08.087
Enzyme name: Orf1
Group: WbwH
UniProt ID: A0A0A6ZF38

Gene name: wbiN
Gene cluster ID: AB812061
Synthesized dimer: aDGalpN(1-3)aDGalpN


Status: predicted in silico
Confirmation methods: in silico
ID: 2835
Organism (ID 1508): Escherichia coli O142

Full structure (ID 2680):

CSDB ID(s): 30056, 22382, 20685, 3113, 1884

Molecule role: O-antigen

Iguchi et al. 2015
DOI: 10.1093/dnares/dsu043
Enzyme name: Gtr50K57
Enzyme GenBank ID: ARR95890.1

Gene name: gtr50
Gene cluster ID: KY434631.1
Synthesized dimer: aDGalpN(1-3)aDGalpN


Donor (ID 34385): Ac(1-2)?DGalpN(1-P-P-5)xXnucU

Acceptor (ID 34970): Ac(1-2)aDGalpN(1-P-P-1)Subst // Subst = undecaprenol

Status: predicted in silico
Confirmation methods: Sequencing (gene, protein)
ID: 3695
Notes: gene cluster name: KL57; name was augmented to make it unique
Organism (ID 7729): Acinetobacter baumannii BAL_212

Full structure (ID 2088):

CSDB ID(s): 494, 6742, 12920, 27754, 30935

Molecule role: CPS

Kenyon et al. 2018
DOI: 10.1099/mic.0.000598

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