CSDB glycosyltransferase search

1 glycosyltransferase activity has been found.
Please note that CSDB GT database covers only a few species: Arabidopsis thaliana, Escherichia coli, Saccharomyces cerevisiae, Acinetobacter baumannii.

Enzyme / Gene Activity Object References
Enzyme name: alg5p
UniProt ID: P40350*
CAZy family: GT2

Gene name: ALG5
Gene GenBank ID: 855874*
Synthesized dimer: bDGlcp(1-?)P


Donor (ID 33616): aDGlcp(1-P-P-5)xXnucU

Acceptor (ID 34774): P-1)Subst // Subst = dolichol

Status: direct evidence in vivo
Confirmation methods: mutation; in vitro (membrane preparation); overexpression; expression in E.coli
ID: 265
Notes: Overexpression of Alg5p in both yeast and Escherichia coli results in an increase
of UDP-glucose : dolichyl-phosphate glucosyltransferase activity. The ALG5 locus
encodes Dol-P-Glc synthase, and its inactivation results in the inability of cells
to synthesize Dol-P-Glc
Organism (ID 11119,16662,16724,16862,16963,16964,16965,16966,16967,16968,16969,16970,16971): Saccharomyces cerevisiae YG0091, SS328, PRY98, DBY746, SS328xSS330, YG0022, YG0092, YG0093, YG0094, YG0095, FC2a, YG92, YG409
Expressed in: E. coli

Exact full structure is unknown

Molecule role (precursor of): N-glycan

Heesen et al. 1994
DOI: 10.1111/j.1432-1033.1994.tb19996.x

Huffaker et al. 1983
DOI: 10.1073/pnas.80.24.7466

Burda et al. 1996
DOI: 10.1073/pnas.93.14.7160

Imbach et al. 1999
DOI: 10.1073/pnas.96.12.6982

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