4 glycosyltransferase activities have been found.
Please note that CSDB GT database covers only a few species: Arabidopsis thaliana, Escherichia coli, Saccharomyces cerevisiae, Acinetobacter baumannii.
| Enzyme / Gene | Activity | Object | References |
|---|---|---|---|
| Enzyme name: ugt51p UniProt ID: Q06321* CAZy family: GT1 Gene name: ATG26/UGT51 Gene GenBank ID: 850886* | Synthesized dimer: bDGlcp(1-3)Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Donor (ID 33616): aDGlcp(1-P-P-5)xXnucU Acceptor (ID 34897): Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Status: semi-direct evidence in vivo Confirmation methods: mutation; expression in E. coli; in vitro (homogenate); in vitro (membrane preparation) ID: 301 Notes: UGT51 gene encodes UDP-glucose:sterol glucosyltransferase which can use different sterols such as cholesterol, sitosterol, and ergosterol as sugar acceptors | Organism (ID 17220): Saccharomyces cerevisiae UTL-7A Expressed in: E. coli Full structure (ID 34898): Molecule role: membrane glycolipid | Warnecke et al. 1999 DOI: 10.1074/jbc.274.19.13048 |
| Synthesized dimer: bDGlcp(1-3)Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Donor (ID 33616): aDGlcp(1-P-P-5)xXnucU Acceptor (ID 34897): Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Status: semi-direct evidence in vivo Confirmation methods: mutation; expression in E. coli; in vitro (homogenate); in vitro (membrane preparation) ID: 514 Notes: UGT51 gene encodes UDP-glucose:sterol glucosyltransferase which can use different sterols such as cholesterol, sitosterol, and ergosterol as sugar acceptors | Organism (ID 12218): Avena sativa Expressed in: E. coli Full structure (ID 34898): Molecule role: membrane glycolipid | ||
| Synthesized dimer: bDGlcp(1-3)Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Donor (ID 33616): aDGlcp(1-P-P-5)xXnucU Acceptor (ID 34897): Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Status: semi-direct evidence in vivo Confirmation methods: mutation; expression in E. coli; in vitro (homogenate); in vitro (membrane preparation) ID: 519 Notes: UGT51 gene encodes UDP-glucose:sterol glucosyltransferase which can use different sterols such as cholesterol, sitosterol, and ergosterol as sugar acceptors | Organism (ID 9097): Dictyostelium discoideum Expressed in: E. coli Full structure (ID 34898): Molecule role: membrane glycolipid | ||
| Synthesized dimer: bDGlcp(1-3)Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Donor (ID 33616): aDGlcp(1-P-P-5)xXnucU Acceptor (ID 34897): Subst // Subst = tomatidine = SMILES C[C@H]1CC[C@@]2(O[C@@]3([H])C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C{3}[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)C3[C@@H]2C)NC1 Status: semi-direct evidence in vivo Confirmation methods: mutation; expression in E. coli; in vitro (homogenate); in vitro (membrane preparation) ID: 524 Notes: UGT51 gene encodes UDP-glucose:sterol glucosyltransferase which can use different sterols such as cholesterol, sitosterol, and ergosterol as sugar acceptors | Organism (ID 10327): Pichia pastoris Expressed in: E. coli Full structure (ID 34898): Molecule role: membrane glycolipid |