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Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: infection due to Klebsiella [ICD11: XN620

]

The structure was elucidated in this paper
Publication DOI: 10.1016/S0008-6215(00)80879-4
Journal NLM ID: 0043535
Publisher: Elsevier
Institutions: Department of Chemistry, University of British Columbia, Vancouver, V6T 1W5 Canada

By using the techniques of methylation analysis, uronic acid degradation, partial hydrolysis, and periodate oxidation, the structure of the capsular polysaccharide from Klebsiella serotype K70 has been investigated. Nuclear magnetic resonance was used extensively to characterize fragments obtained as a result of the various degradation procedures. The existence of a linear, hexasaccharide repeating unit having a 1-carboxyethylidene group attached to a 2-linked α-l-rhamnosyl residue in every second repeating unit has been demonstrated.

Structure type: oligomer
Location inside paper: p.325, structure 2
Compound class: CPS
Contained glycoepitopes: IEDB_136044,IEDB_136105,IEDB_137472,IEDB_141794,IEDB_141798,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_190606,IEDB_225177,IEDB_885823,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_7,SB_88

Methods: 13C NMR, 1H NMR, methylation, periodate oxidation, GLC-MS, partial acid hydrolysis, sugar analysis, GLC, Smith degradation, paper chromatography, GPC, ion-exchange chromatography, optical rotation measurement, GPCX
Comments, role: oligosaccharide was obtained from the partial acid hydrolysis of the CPS

Related record ID(s): 113310
NCBI Taxonomy refs (TaxIDs): 576
Reference(s) to other database(s): GTC:G18515JN, GlycomeDB:4891
Show glycosyltransferases

There are 3 chemically distinct structures. Please, select:

C[C@@H]1OC(O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]2O)[C@H](O)[C@H]1O

SVG MW SMILES 3D mol Ionize

Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: infection due to Klebsiella [ICD11: XN620

Structure type: polymer chemical repeating unit
Location inside paper: p.329
Compound class: CPS
Contained glycoepitopes: IEDB_115136,IEDB_133754,IEDB_136044,IEDB_136105,IEDB_137472,IEDB_140630,IEDB_141794,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_190606,IEDB_225177,IEDB_423153,IEDB_885823,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_7,SB_88

Methods: 13C NMR, 1H NMR, methylation, periodate oxidation, GLC-MS, partial acid hydrolysis, sugar analysis, GLC, Smith degradation, paper chromatography, GPC, ion-exchange chromatography, optical rotation measurement, GPCX

Related record ID(s): 113309
NCBI Taxonomy refs (TaxIDs): 576
Show glycosyltransferases

There is only one chemically distinct structure:

[*]O[C@@H]1[C@@H](C(=O)O)O[C@@H](O[C@H]2[C@H](C)O[C@@H](O[C@H]3[C@H](O[C@@H]4[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]4O[C@H]4[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]5[C@H]([*])O[C@@H](C)[C@@H]6OC(C)(C(=O)O)O[C@@H]56)[C@@H]4O)O[C@@H](C)[C@H](O)[C@H]3O)[C@H](O)[C@@H]2O)[C@H](O)[C@H]1O

SVG MW SMILES 3D mol Ionize