Novel acyl glyco-carotenoic acids, diapolycopenedioic acid xylosyl esters A, B, and C, were isolated as red pigments by using chromatographic methods from a marine bacterium, Rubritalea squalenifaciens, belonging to subdivision 1 of Verrucomicrobia. The structures of these diapolycopenedioic acid xylosyl esters were determined to be 4-[2-O-acyl-β-D-xylopyranosyl] hydrogen 4,4'-diapo-Ψ,Ψ-carotene-4,4'-dioate by spectroscopic analysis. Diapolycopenedioic acid xylosyl ester A showed potent antioxidative activity in a 1O2 suppression model
Rubritalea squalenifaciens, diapolycopenedioic acid xylosyl ester, antioxidative activity
NCBI PubMed ID: 18503197Publication DOI: 10.1038/ja.2008.28Journal NLM ID: 0151115Publisher: London: Nature Publishing Group
Correspondence: kshindo@fc.jwu.ac.jp
Institutions: Department of Food and Nutrition, Japan Women's University, Bunkyo-ku, Japan, Marine Biotechnology Institute, Heita, Japan, Reseach Institute for Production Development, Shimogano-morimoto-cho, Japan
Methods: 13C NMR, 1H NMR, NMR-2D, FAB-MS, inhibition studies, methanolysis, HPLC, UV, extraction, optical rotation measurement, CC, cell growth, HR-ESI-MS, antioxidant activities, centrifugation