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Structure type: monomer ; 439.1876 [M+H]+
C₂₄H₂₆O₆N₂
Trivial name: phenazoviridin
Compound class: glycoside

• Article ID: 5718
  Kato S, Shindo K, Yamagishi Y, Matsuoka M, Kawai H, Mochizuki J "Phenazoviridin, a novel free radical scavenger from Streptomyces sp. Taxonomy, fermentation, isolation, structure elucidation and biological properties" - The Journal of Antibiotics 46(10) (1993) 1485-1493
  

  Phenazoviridin is a newly discovered free radical scavenger from microorganisms. It was isolated from the culture of Streptomyces sp. HR04. The structure of phenazoviridin was determined as 6-(3-methyl-2-butenyl)phenazine-1-carboxylic acid 6-deoxy-α-L-talopyranose ester on the basis of its spectroscopic and physico-chemical properties. The novel substance showed strong inhibitory activity against lipid peroxidation in rat brain homogenate and exhibited antihypoxic activity in mice.

  phenazoviridin, Streptomyces sp. HR04, radical scavenging

  NCBI PubMed ID: 8244877
  Publication DOI: 10.7164/antibiotics.46.1485
  Journal NLM ID: 0151115
  Publisher: London: Nature Publishing Group
  Institutions: Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd., Takasaki, Japan
  Methods: 13C NMR, 1H NMR, IR, inhibition studies, TLC, acid hydrolysis, biological assays, alkaline hydrolysis, UV, extraction, optical rotation measurement, CC, cell growth, melting point determination, HR-FAB-MS, refractometry
  
   
  
  Streptomyces sp. HR04
  CSDB ID 51127 (all data & tools)