Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: periodontitis [ICD11:
DA0C 
]
NCBI PubMed ID: 20457448Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: J. Zhang <zhangjianjun
cau.edu.cn>
Institutions: Key Lab of Pesticide Chemistry and Application Technology, Department of Applied Chemistry, China Agricultural University, Beijing, China
Concise synthesis of a 6-deoxy-α-L-talose tetrasaccharide, 6-deoxy-α-L-Talp-(1→3)-6-deoxy-α-L-Talp-(1→2)-6-deoxy-α-L-Talp-(1→3)-6-deoxy-α-L-Talp, the dimer of the disaccharide repeating unit of the OPS from Aggregatibacter actinomycetemcomitans serotype c, has been accomplished through suitable protecting group manipulations and stereoselective glycosylation starting from commercially available L-rhamnose. The target oligosaccharide in the form of its p-methoxyphenyl glycoside is suitable for further glycoconjugate formation via selective cleavage of this group.
tetrasaccharide, rhamnose, selective acylation, 6-deoxya-L-talose
Structure type: polymer chemical repeating unit
Location inside paper: p.1230
Trivial name: c-specific polysaccharide antigen
Compound class: O-polysaccharide
Methods: NMR, chemical synthesis, selective acylation
Synthetic data: chemical
Related record ID(s): 25554
NCBI Taxonomy refs (TaxIDs): 714Reference(s) to other database(s): GTC:G63295ZU
Show glycosyltransferases
There is only one chemically distinct structure:
Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: periodontitis [ICD11:
DA0C ]
The structure was elucidated in this paperNCBI PubMed ID: 20457448Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: J. Zhang <zhangjianjun
cau.edu.cn>
Institutions: Key Lab of Pesticide Chemistry and Application Technology, Department of Applied Chemistry, China Agricultural University, Beijing, China
Concise synthesis of a 6-deoxy-α-L-talose tetrasaccharide, 6-deoxy-α-L-Talp-(1→3)-6-deoxy-α-L-Talp-(1→2)-6-deoxy-α-L-Talp-(1→3)-6-deoxy-α-L-Talp, the dimer of the disaccharide repeating unit of the OPS from Aggregatibacter actinomycetemcomitans serotype c, has been accomplished through suitable protecting group manipulations and stereoselective glycosylation starting from commercially available L-rhamnose. The target oligosaccharide in the form of its p-methoxyphenyl glycoside is suitable for further glycoconjugate formation via selective cleavage of this group.
tetrasaccharide, rhamnose, selective acylation, 6-deoxya-L-talose
Structure type: oligomer
Location inside paper: p.1230, fig.1, 1
Aglycon: p-methoxyphenyl
Methods: NMR, chemical synthesis, selective acylation
Synthetic data: chemical
Related record ID(s): 25201
NCBI Taxonomy refs (TaxIDs): 714Reference(s) to other database(s): GTC:G96383IU
Show glycosyltransferases
There is only one chemically distinct structure:
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