The ethyl acetate soluble fraction obtained from the acetone extract of fresh Calluna vuloaris heather flowers afforded a mixture of two minor 2,3-dihydroflavonoid glucosides. Separations were achieved by column chromatography on polyamide as well as by reversed phase MPLC and HPLC. Structural elucidations were performed by UV, 1H and 13C NMR. The two novel compounds which are related to the major constituent, callunin were identified as 3-desoxycallunin and 2"-acetylcallunin. This is the first report of a flavanone 8-glucoside and the second report of a dihydroflavonol 8-glucoside in the plant kingdom.
7, 8, Calluna vulgaris, Ericaceae, callunin, heather fowers, (2R, 3R)-5, 4'-tetrahydroxydihydroflavonol 8-glucoside, 2"-acetylcallunin, 4'-tetrahydroxydihydroflavonol 8-(2"-acetylglucoside), 3-desoxycallunin, (2R)-5, 4'-tetrahydroxyflavanone 8-glucoside
Journal NLM ID: 0151434Publisher: Elsevier
Institutions: Laboratoire de Chimie des Substances Naturelles, Universite de Limoges, Limoges, France, Equipe Biomolecules, Laboratoire de Pharmacognosie et de Phytochimie, Laboratoire de Chimie Physique, UFR de Pharmacie, Universite de Limoges, Limoges, France
Methods: 13C NMR, 1H NMR, TLC, UV
Found