Ten phenolic compounds were isolated from a butanol fraction of sage extracts. Their structures were determined by spectral methods (NMR, MS, IR). Among them, a novel compound, 4-hydroxy-acetophenone-4-O-beta-D-apiofuranosyl-(1-->6) was identified. Two test systems, DPPH free radical scavenging activity and radical cation ABTS(.+) scavenging activity, were used to evaluate their antioxidant activity. The most active compounds were found to be rosmarinic acid and luteolin-7-O-beta-glucopyranoside.
Antioxidant activity, phenolic compounds, sage, Salvia officinalis
Publication DOI: 10.1021/jf980614bJournal NLM ID: 0374755Publisher: American Chemical Society
Institutions: Department of Food Science, Cook College, Rutgers University, New Brunswick, New Jersey, USA, Department of Pharmaceutical Chemistry, College of Pharmacy, Rutgers University, Piscataway, New Jersey, USA, Department of Food Science and Technology, National Pingtung University of Science and Technology, Pingtung, Taiwan
Methods: 13C NMR, 1H NMR, FAB-MS, extraction, optical rotation measurement, DCI-MS, CC, FT-IR