Two new aporphine glycosides, stesakine-9-O-β-d-glucopyranoside (1) and N-methylasimilobine-2-O-β-d-glucopyranoside (2), were isolated from the seeds of Stephania cepharantha cultivated in Japan, together with 16 known alkaloids. The structures of 1 and 2 were spectroscopically determined by comparison of their 1H and 13C NMR data with those of stesakine (11) and N-methylasimilobine (12), respectively.
NCBI PubMed ID: 10785417Publication DOI: 10.1021/np990469bJournal NLM ID: 7906882Publisher: American Society of Pharmacognosy
Correspondence: kasiwaba@ac.shoyaku.ac.jp
Institutions: Research Laboratories, Kaken Shoyaku Co., Ltd., Tokyo, Japan, Showa Pharmaceutical University, Machida, Japan
Methods: 13C NMR, 1H NMR, NMR-2D, IR, FAB-MS, extraction, optical rotation measurement, CC, melting point determination, evaporation, HR-FAB-MS, PTLC
Found