Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
NCBI PubMed ID: 30223056Publication DOI: 10.1016/j.ijbiomac.2018.09.080Journal NLM ID: 7909578Publisher: Butterworth-Heinemann
Correspondence: Lv S <lvshanshan
mail.buct.edu.cn>
Institutions: State Key Laboratory of Organic-Inorganic Composite Materials, Beijing University of Chemical Technology, Beijing, China
In order to develop pullulan/gelatin-based gels as potential extracellular matrix-mimetic scaffolds, a "one-step" synthesis method using 1,1'-carbonyldiimidazole (CDI) as activator in DMSO under mild conditions was reported for the first time. Particularly, in contrast to conventional critical requirement of absolute dryness for CDI, it was interesting to find that the formation of gels could be accomplished in the presence of aqueous solvent within a much shorter time, while obtaining improved mechanical properties as demonstrated by compressive tests. UV-Visible spectroscopy, NMR spectrum, TEM and SEM analysis have been employed to evaluate the underlying reaction mechanisms. This method implied that absolute dryness might not be necessary for using CDI as activator in certain cases. This method also represents a new rapid and efficient approach for synthesizing a great variety of chemically crosslinked polysaccharide/protein-based gels as promising material platform potential for tissue engineering and drug delivery applications.
1, pullulan, gels, 1′-carbonyldiimidazole, gelatin, nano-gels
Structure type: polymer chemical repeating unit
Location inside paper: abstract
Trivial name: pullulan
Compound class: EPS, O-polysaccharide, cell wall polysaccharide, glucan, polysaccharide
Contained glycoepitopes: IEDB_140629,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_420419,IEDB_420420,IEDB_420421,IEDB_857742,IEDB_983931,SB_192
Methods: 1H NMR, chemical synthesis, UV, spectrophotometry, SEM, evaporation, TEM, dynamic mechanical analysis
Related record ID(s): 11749, 40013, 41763, 41825, 43176, 43316, 43373, 43378, 43380, 43437, 43459, 44407, 44460, 44465, 44466, 44471, 44474, 44482, 44484, 44494, 45035, 45814, 45934, 45961, 46041, 46508, 47851, 48389, 48424, 48425, 48441, 48447, 48467, 48468, 48469, 48643, 48730, 48783, 49231, 49289, 49953, 49977, 49978, 49979, 49995, 49999, 50002, 50007, 50014, 50071, 50081, 50082, 50083, 50111, 50113, 104020, 112375, 113049, 122344, 139861, 143683, 143686, 143688, 231871
NCBI Taxonomy refs (TaxIDs): 5580Reference(s) to other database(s): GTC:G71532WE, CCSD:
45938, CBank-STR:4859, GenDB:KY767023; GenDB:KY767024
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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