Taxonomic group: fungi / Basidiomycota
(Phylum: Basidiomycota)
Publication DOI: 10.1007/s12221-019-9388-8Publisher: Springer
Correspondence: Jrashidiyani
gmail.com
Institutions: Nanobiotechnology Research Center, Baqiyatallah University of Medical Science, Tehran, Iran, Department of Life Sciences Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran, Chemical Engineering Group, Faculty of Petroleum and Petrochemical Engineering, Hakim Sabzevari University, Sabzevar, Iran
The use of natural polymers and electrospinning as a new method of wound dressing production is one of the things that can revolutionize the medical world. Due to the importance of wound healing and characteristics such as anti-inflammatory and antimicrobial properties, it is possible to use natural compounds such as fungi and metabolites derived from them to produce wound dressing. In this study, schizophyllan (SPG) as an extracellular polysaccharide was extracted from Iranian Schizophyllum commune (NCBI MG761830) and then the silver nanoparticles (AgNPs) were produced by the in-situ method in 1.5 % SPG solution. Afterward, they were combined with polyvinyl alcohol 10 % (PVA) polymer to strengthen the fiber structure. We investigated the properties of nanofibers containing PVA/SPG-AgNPs and PVA/SPG20 %. The physicochemical properties of two fibers were investigated by SEM, TEM, FTIR, contact angle, water uptake, nanoparticle release, and biological test (antibacterial, and MTT). The diameter of the nanofiber-containing the AgNPs was about 169 nm and the other nanofiber was about 212 nm. The highest inhibition of the growth of the bacterium by PVA/SPG-AgNPs against E. coli and S. aureus was about 88.34 % and 64.7 %, respectively. The silver ion release from PVA/SPG-AgNPs nanofibers was 21 μg/ml after fifth day. Both nanofibers had no toxic effect on L929 fibroblast cells.
cytotoxicity, in situ, schizophyllan, nanofiber, silver nanoparticle
Structure type: polymer chemical repeating unit
Location inside paper: abstract, Fig. 1
Trivial name: β-D-glucan, β-glucan, schizophyllan, carboxymethylglucan, pleuran, scleroglucan, lentinan, GRN, SPG, sizofiran, shizophyllan, Scleroglucan, lentinan-type beta-glucans (Ths-2), b-(1-3,6)-glucan, HEP3, grifolan LE, schizophyllan, scleroglucan, lentinan, termitan, grifolan, schizophyllan, scleroglucan, schizophyllan, sizofiran, grifolan, scleroglucan, schizophyllan, sonifilan, schizophyllan, grifolan, G. frondosa polysaccharide (GFP), alkali-soluble β-glucan (PeA3), schizophyllan (SPG), β-glucan, schizophyllan, β-glucan
Compound class: EPS, O-polysaccharide, cell wall polysaccharide, glucan, polysaccharide, β-glucan, b-glucan, D-glucan, scleroglucan
Contained glycoepitopes: IEDB_1397514,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_241101,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Methods: IR, X-ray, extraction, cell growth, antibacterial assay, dynamic light scattering, cell viability assay, cytotoxicity assay, spectrophotometry, TEM, FESEM, ICP-AES, electrospinning, conductometry
Related record ID(s): 40416, 40443, 41288, 41375, 41715, 41772, 41780, 41806, 41823, 41836, 41851, 42116, 42117, 42403, 42490, 43304, 43381, 43382, 43481, 43699, 43786, 43939, 43969, 44278, 44415, 44459, 44487, 44604, 45400, 45411, 45412, 45414, 45416, 45524, 45557, 45559, 45575, 45616, 45617, 45743, 45813, 45872, 45929, 47495, 47536, 48401, 48481, 48673, 48964, 49259, 49988, 50026, 50061, 50064, 50089, 100204, 106270, 110131, 111427, 111916, 112939, 113003, 115217, 115506, 116379, 118305, 125411, 139900, 140142, 141782, 144184, 296738
NCBI Taxonomy refs (TaxIDs): 5334Reference(s) to other database(s): GTC:G66305IS, CCSD:
49943, CBank-STR:12679, CA:9050-67-3
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There is only one chemically distinct structure:
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