Taxonomic group: plant / Streptophyta
(Phylum: Streptophyta)
Organ / tissue: flower
NCBI PubMed ID: 11091001Publication DOI: 10.1016/s0378-8741(00)00327-5Journal NLM ID: 7903310Publisher: Limerick: Elsevier Sequoia
Correspondence: yesilada
tr-net.net.tr
Institutions: Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey, Tokushima University, Faculty of Pharmaceutical Sciences, Tokushima, Japan
Spartium junceum L. (Fabaceae) flowers are used for the treatment of peptic ulcers in Turkish folk medicine. The possible superoxide dismutase-like activity of the extracts, fractions and constituents obtained through activity-guided fractionation were studied by using in vitro electron spin resonance spectrometry, in order to explain the role of antioxidant principles in the potent antiulcerogenic activity of the extract. Despite the fact that the triterpene, spartitrioside, which was previously reported as the active antiulcerogenic constituent of the flowers was found almost inactive, the flavonoid-rich fractions showed potent antioxidant activity. Five flavonoid glycosides bearing catechol structure in ring B were isolated from the butanol extract and their structures were elucidated using 1H- and 13C-NMR techniques as isoquercitrin (quercetin 3β-glucoside) (1,); luteolin 4’β-glucoside (2); quercetin 3, 4′-diglucoside (3); azaleatin 3β-glucoside (quercetin 5-methylether 3β-glucoside) (4), quercetin 4′β-glucoside (5). Flavonoids (2) and (4) showed the highest in vitro antioxidant activity with 22.59 and 19.08 U/ml, respectively.
electron spin resonance; Spartium junceum; antioxidant activity; superoxide dismutase-like activity; spin trapping; superoxide radical
Structure type: monomer
Location inside paper: p. 477, Fig. 3, structure 1
Trivial name: isoquercitrin
Compound class: saponin glycoside, glycoside, flavonoid glycoside, flavonol glycoside, flavone glycoside
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, NMR-2D, FAB-MS, TLC, ESI-MS, biological assays, HPLC, extraction, column chromatography, antioxidant activities, ESR
Related record ID(s): 68742, 68743, 68744, 68745
NCBI Taxonomy refs (TaxIDs): 49843Reference(s) to other database(s): CCSD:
49965, CBank-STR:953
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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