CSDB glycosyltransferase search

4 glycosyltransferase activities have been found.
Please note that CSDB GT database covers only a few species: Arabidopsis thaliana, Escherichia coli, Saccharomyces cerevisiae, Acinetobacter baumannii.

Enzyme / Gene Activity Object References
Enzyme name: WzY
UniProt ID: P27835*
Synthesized dimer: aDGalpN(1-2)aDGalp


Donor (ID 34539): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = 3,7,11,15,19,23,27,31,35,39,43-undecamethyl-tetratetraconta-2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E,42-undecaen-1-ol

Acceptor (ID 34539): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = 3,7,11,15,19,23,27,31,35,39,43-undecamethyl-tetratetraconta-2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E,42-undecaen-1-ol

Status: evidence in vitro
Confirmation methods: in vitro (purified protein)
ID: 2263
Notes: Wzy acts as an O-antigen polymerase. An exemplary structure is shown.
Organism (ID 2516): Escherichia coli O86:B7

Full structure (ID 34540):

Molecule role: O-antigen

Woodward et al. 2010
DOI: 10.1038/nchembio.351
Synthesized dimer: aDGalpN(1-2)aDGalp


Donor (ID 34541): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = heptaprenol (4cis, 2trans)

Acceptor (ID 34541): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = heptaprenol (4cis, 2trans)

Status: evidence in vitro
Confirmation methods: in vitro (purified protein)
ID: 2264
Notes: Wzy acts as an O-antigen polymerase. An exemplary structure is shown.
Organism (ID 2516): Escherichia coli O86:B7

Full structure (ID 34542):

Molecule role: O-antigen

Synthesized dimer: aDGalpN(1-2)aDGalp


Donor (ID 34543): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = pentaprenol (2cis, 2trans)

Acceptor (ID 34543): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = pentaprenol (2cis, 2trans)

Status: evidence in vitro
Confirmation methods: in vitro (purified protein)
ID: 2265
Notes: Wzy acts as an O-antigen polymerase. An exemplary structure is shown.
Organism (ID 2516): Escherichia coli O86:B7

Full structure (ID 34544):

Molecule role: O-antigen

Synthesized dimer: aDGalpN(1-2)aDGalp


Donor (ID 34545): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = cis-pentaprenol (4cis, 0trans)

Acceptor (ID 34545): aLFucp(1-2)[aDGalp(1-3)]bDGalp(1-3)[Ac(1-2)]aDGalpN(1-3)[Ac(1-2)]aDGalpN(1-P-P-1)Subst // Subst = cis-pentaprenol (4cis, 0trans)

Status: evidence in vitro
Confirmation methods: in vitro (purified protein)
ID: 2266
Notes: Wzy acts as an O-antigen polymerase. An exemplary structure is shown.
Organism (ID 2516): Escherichia coli O86:B7

Full structure (ID 34546):

Molecule role: O-antigen

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