Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
NCBI PubMed ID: 15727817Journal NLM ID: 7705721Publisher: Blackwell Publishing
Correspondence: p.reeves
angis.usyd.edu.au
Institutions: School of Molecular and Microbial Biosciences, University of Sydney, NSW 2006, Australia
Escherichia coli express many types of O antigen, present in the outer membrane of the Gram-negative bacterial cell wall. O-Antigen biosynthesis genes are clustered together and differences seen in O-antigen types are due to genetic variation within this gene cluster. Sequencing of the E. coli O4 O-antigen gene cluster revealed a similar gene order and high levels of similarity to that of E. coli O26; indicating a common ancestor. These lateral transfer events observed within O-antigen gene clusters may occur as part of the evolution of the pathogenic clones.
biosynthesis, transfer, antigen, variation, O-antigen, Escherichia coli, gene cluster, cell wall, sequencing
Structure type: polymer chemical repeating unit
Location inside paper: p.28
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_135813,IEDB_136105,IEDB_137340,IEDB_141807,IEDB_151531,IEDB_225177,IEDB_885823
Methods: genetic methods
Biosynthesis and genetic data: genetic data, biosynthetic data
Related record ID(s): 3199, 10216, 20653, 23615
NCBI Taxonomy refs (TaxIDs): 404399Reference(s) to other database(s): GTC:G67201SZ, GlycomeDB:
25922
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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