Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Brucella abortus [ICD11:
XN7A8 
]
NCBI PubMed ID: 15694858Journal NLM ID: 9815056Publisher: London; New York: Current Biology
Institutions: Centre d'Immunologie INSERM-CNRS-Universite de la Mediterranee, Parc Scientifique de Luminy, Case 906, 13288 Marseille 9, France
Brucella is a facultative intracellular bacterium responsible for brucellosis. Virulence factors involved in Brucella replication and Brucella's strategies to circumvent the immune response are under investigation. VirB proteins that form the type IV secretion system and that are involved in intracellular replication are considered as one of Brucella's virulence factors. In addition to this secretion system, bacterial outer membrane components have also been described as being implicated in Brucella survival in the host. For example, this bacterium possesses an unconventional non-endotoxic lipopolysaccharide that confers resistance to anti-microbial attacks and modulates the host immune response. These properties make lipopolysaccharide an important virulence factor for Brucella survival and replication in the host
Lipopolysaccharide, Bacterial, host, virulence, form, property, type, factor, protein, response, bacteria, Brucella, intracellular, component, resistance, case, membrane, proteins, immune response, outer membrane, virulence factor, immune, France, secretion, antimicrobial, brucellosis, survival
Structure type: homopolymer
Location inside paper: p.61
Trivial name: perosamine homopolymer, perosamine
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_131172,IEDB_134281,IEDB_1397515,IEDB_2116320,IEDB_434547,IEDB_628715
Related record ID(s): 220, 1236, 3181, 5252, 6859, 7225, 7463, 108433, 110473, 122777, 130189, 143514, 148072
NCBI Taxonomy refs (TaxIDs): 235Reference(s) to other database(s): GTC:G55700WU, GlycomeDB:
3393, CCSD:
42651, CBank-STR:4424
Show glycosyltransferases
There is only one chemically distinct structure: