Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Campylobacter jejuni [ICD11:
XN4Q5 
]
NCBI PubMed ID: 16055105Publication DOI: 10.1016/j.carres.2005.06.023Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Department of Chemistry, University of Guelph, Guelph, ON, Canada N1G 2W1, Department of Chemistry, North Carolina Agricultural and Technical State University, Greensboro, NC 27411, USA, Enteric Diseases Department, Naval Medical Research Center, Silver Spring, MD 20910, USA
Campylobacter jejuni infection is a main source of severe gastroenteritis-related illnesses in humans and there is also evidence that it may be linked to neurological disorders. C. jejuni 81-176 is a virulent strain that has become the global model in the study of mechanisms and pathogenesis of C. jejuni infection. For this reason, we were engaged in studying the fine structures of cell-surface carbohydrate antigens of C. jejuni 81-176, namely, the capsule polysaccharide (CPS) and lipooligosaccharide (LOS). Serologically, C. jejuni 81-176 has been classified as belonging to serogroups HS23 and HS36, and indeed previous studies have shown that the LOS and CPS structures possess components similar to those expressed by serostrains HS23 and HS36. Here, we describe that in addition to the LOS and CPS, this strain also produced an independent cell-surface (1→4)-α-glucan capsule
Campylobacter jejuni, capsule, glucan
Structure type: homopolymer
Location inside paper: abstract
Trivial name: methyl glucose lipopolysaccharide, glucan, maltosaccharide, α-1,4-D-glucan, amylose, α-glucan, glycogen backbone, α-(1,4)-glucan, starch, α-(1-4)-glucan, starch, glycogen
Compound class: CPS, EPS, O-polysaccharide, cell wall polysaccharide, glucan, polysaccharide, methyl glucose lipopolysaccharide
Contained glycoepitopes: IEDB_140629,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_420417,IEDB_420418,IEDB_420421,IEDB_857742,IEDB_983931,SB_192
Methods: NMR, sugar analysis, linkage analysis
Related record ID(s): 913, 8387, 10307, 10308, 10309, 10310, 22727, 23997, 102751, 106369
NCBI Taxonomy refs (TaxIDs): 354242Reference(s) to other database(s): GTC:G05740LL, GlycomeDB:
12100, CCSD:
4943, CBank-STR:819
Show glycosyltransferases
[as TSV]
13C NMR data:
missing...
1H NMR data:
Linkage Residue H1 H2 H3 H4 H5 H6
aDGlcp 5.42 3.64 3.98 3.66 ? ?
1H NMR data:
| Linkage | Residue | H1 | H2 | H3 | H4 | H5 | H6 |
|---|
| | aDGlcp | 5.42 | 3.64 | 3.98 | 3.66 | ? | ? |
|
There is only one chemically distinct structure:
Found 
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(later renamed to: Campylobacter jejuni subsp. jejuni 81-176)