Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Acinetobacter [ICD11:
XN25B 
]
Journal NLM ID: 7901356WWW link: http://www.ichf.edu.pl/pjch/pj-2005/pj-2005-02c.pdfPublisher: PaĆstwowe Wydawnictwo Naukowe
Institutions: Divisions of Biochemical Microbiology, Structural Biochemistry, Research Center Borstel, Leibniz Center for Medicine and Biosciences, D-23845 Borstel, Germany
Extraction of dry bacteria of Acinetobacter strain 44 (DNA group 3) by phenol/water gave a polymer that was identified by means of serological studies as S-form lipopolysaccharide (LPS). Mild acetic acid hydrolysis degraded the O-specific polysaccharide, thus, its structure was investigated by compositional analyses and NMR spectroscopy after de-O-acylation and Smith degradation of the LPS. The structure of the O-specific polysaccharides was: [see formula in the text]. After immunization of BALB/c mice with Acinetobacter strain 44, monoclonal antibody S48-26 (IgG3 isotype) was obtained which reacted in Western blot with this LPSZ and characterized it as S-form.
Lipopolysaccharide, structure, DNA, strain, polysaccharide, repeating unit, group, Acinetobacter, O-polysaccharide, O polysaccharide, O-specific, O-specific polysaccharide, tyvelose, Enterobacter
Structure type: oligomer
Location inside paper: p.270
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_135610,IEDB_135813,IEDB_136105,IEDB_137340,IEDB_141807,IEDB_151531,IEDB_225177,IEDB_885823
Methods: NMR, Smith degradation, composition analysis
Biological activity: serological data
Related record ID(s): 10181, 10465, 10466
NCBI Taxonomy refs (TaxIDs): 472Reference(s) to other database(s): GTC:G78367GH
Show glycosyltransferases
There is only one chemically distinct structure: