Taxonomic group: protista / Euglenozoa
(Phylum: Euglenozoa)
Host organism: (mammal)
Organ / tissue: Life stage: metacyclic formAssociated disease: Chagas disease [ICD11:
1F53 
, ICD11:
XN56V ];
infection due to Trypanosoma cruzi [ICD11:
XN56V ]
NCBI PubMed ID: 35536961Publication DOI: 10.1101/glycobiology.4e.43Publisher: Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press
Editors: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Mohnen D, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger RH
Correspondence: R.D. Cummings <rcummin1
bidmc.harvard.edu>
Institutions: Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA, Department of Molecular Cell Biology & Immunology, VU University Center, Amsterdam, The Netherlands
Parasitic protozoans and helminths (worms) synthesize glycans with structures often different from those typically found in vertebrates, and are thus often antigenic. Parasites also express glycan-binding proteins (GBPs) involved in host invasion and parasitism. As part of the disease process, parasite glycans can trigger the host's innate immune system, which can lead to the induction of adaptive immune responses. This chapter discusses the major roles of glycoconjugates in parasitic infections.
Structure type: oligomer
Location inside paper: Fig. 43.3, LPPG
Trivial name: GIPL, LPPG
Compound class: lipopeptidophosphoglycan, glycoinositol phospholipid
Contained glycoepitopes: IEDB_130701,IEDB_136095,IEDB_136104,IEDB_137472,IEDB_140116,IEDB_141793,IEDB_141807,IEDB_141829,IEDB_141830,IEDB_141832,IEDB_143632,IEDB_144983,IEDB_151531,IEDB_152206,IEDB_153220,IEDB_190606,IEDB_76933,IEDB_983930,SB_136,SB_191,SB_196,SB_198,SB_44,SB_67,SB_72
Comments, role: Bookshelf ID: NBK579956, (no PDF, only Internet) review
NCBI Taxonomy refs (TaxIDs): 5693
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error