Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Shigella sonnei [ICD11:
XN9M9 
];
infection due to Shigella flexneri [ICD11:
XN7Y2 ];
infection due to Escherichia coli [ICD11:
XN6P4 ]
The structure was elucidated in this paperNCBI PubMed ID: 26656001Publication DOI: 10.1016/j.mimet.2015.12.004Journal NLM ID: 8306883Correspondence: g.larrouy-maumus
imperial.ac.uk
Institutions: MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, UK, MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London, London, UK
The purification and characterization of Gram-negative bacterial lipid A is tedious and time-consuming. Herein we report a rapid and sensitive method to identify lipid A directly on intact bacteria without any chemical treatment or purification, using an atypical solvent system to solubilize the matrix combined with MALDI-TOF mass spectrometry.
lipid A, mass spectrometry, Gram-negative bacteria, endotoxins
Structure type: oligomer ; 1796.2 [M-H]-
Location inside paper: p.70, fig.2A
Compound class: lipid A
Contained glycoepitopes: IEDB_135394,IEDB_135515,IEDB_141807,IEDB_151531,IEDB_176772,IEDB_534864
Methods: MALDI-TOF MS
Related record ID(s): 11602, 11603
NCBI Taxonomy refs (TaxIDs): 216599,
623,
562
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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