Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: bacillary dysentery (shigellosis) [ICD11:
1A02 
, ICD11:
SA56 , ICD11:
XN7HG ];
infection due to Shigella dysenteriae [ICD11:
XN285 ]
Publication DOI: 10.1080/07328303.2015.1108424Journal NLM ID: 8218151Publisher: Marcel Dekker
Correspondence: Anup Kumar Misra <akmisra69
gmail.com>
Institutions: Bose Institute, Division of Molecular Medicine, P-1/12, C.I.T. Scheme VII-M, Kolkata-700054, India
A disaccharide and a trisaccharide fragment related to the cell wall O-polysaccharide of Shigella dysenteriae type 8 have been synthesized in a minimum number of steps using recently reported reaction conditions. Stereoselective 1,2-cis glycosylation and late-stage selective oxidation of the primary hydroxyl group to the carboxylic group are key features of the synthetic strategy. The yields of the glycosylation reactions are excellent with high stereoselectivity.
glycosylation, Shigella dysenteriae, glycosides, oxidation, stereoselective
Structure type: polymer chemical repeating unit
Location inside paper: p.502, fig.1
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_115136,IEDB_130648,IEDB_137340,IEDB_137473,IEDB_140630,IEDB_141807,IEDB_142488,IEDB_146664,IEDB_151531,IEDB_153510,IEDB_423153,IEDB_983931,SB_192
Methods: 13C NMR, 1H NMR, NMR-2D, IR, TLC, ESI-MS, MALDI-MS, chemical synthesis, chemical methods, CD, glycosylations
Comments, role: published polymerization frame was shifted for conformity with other records.
NCBI Taxonomy refs (TaxIDs): 622Reference(s) to other database(s): GTC:G58219BX, GlycomeDB:
36884
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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