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Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11: XN6P4

]

The structure was elucidated in this paper
Publication DOI: 10.1016/S0008-6215(00)84816-8
Journal NLM ID: 0043535
Publisher: Elsevier
Institutions: Department of Organic Chemistry, Arrhenius Laboratory, University of Stockholm, S-104 05 Stockholm, Sweden, Department of Bacteriology, National Bacteriological Laboratory, S-105 21 Stockholm, Sweden

Escherichia coli C is an R-strain, and hence its lipopolysaccharide consists only of lipid A joined to a basal core. Intact core-polysaccharides have been prepared from this strain, and from mutants of the same strain defective in various stages of core biosynthesis. Using sugar and methylation analyses, and chemical and enzymic degradations, the hexose region of the core of the parent strain has been shown to be a pentasaccharide for which the following structure is proposed [formula: see text].

Structure type: oligomer
Location inside paper: abstract, structure 2
Aglycon: (->7) Hep+Kdo+Lipid A
Compound class: LPS
Contained glycoepitopes: IEDB_131186,IEDB_135818,IEDB_136906,IEDB_137472,IEDB_141794,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_151528,IEDB_153755,IEDB_190606,IEDB_983931,SB_192,SB_7

Methods: methylation, GLC-MS, gel filtration, sugar analysis, GLC, enzymatic degradation, optical rotation measurement

Related record ID(s): 113238, 113240
NCBI Taxonomy refs (TaxIDs): 498388, 562
Reference(s) to other database(s): GTC:G99516CU, GlycomeDB:4841
Show glycosyltransferases

There is only one chemically distinct structure:

OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@H](O[C@@H]3[C@@H](O)[C@H](O)O[C@H](CO)[C@H]3O)[C@@H]2O[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

SVG MW SMILES 3D mol Ionize