Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Shigella flexneri [ICD11:
XN7Y2 
];
infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperNCBI PubMed ID: 371805Publication DOI: 10.1016/S0008-6215(00)83786-6Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Department of Organic Chemistry, Arrhenius Laboratory, University of Stockholm, Stockholm, Sweden, Department of Bacteriology, National Bacteriological Laboratory, Stockholm, Sweden
The structure of the hexose region of the Enterobacteriaceae type R3 core polysaccharide, which is the common core in Shigella flexneri and some Escherichia coli lipopolysaccharides (LPS), has been investigated. The principal method used in these studies involved methylation analysis of the original and modified materials. The polysaccharide was modified by N-deacetylation-deamination and by Smith degradation. As a result of these studies, the following structure is proposed: α-D-Glcp-(1→2)-α-D-Glcp-(1→2)-[α-D-GlcNAcp-(1→3)]-α-D-Galp-(1→3)-α-D-Glcp-(1→.
Structure type: oligomer
Location inside paper: 4
Trivial name: outer core type R3
Compound class: core oligosaccharide, LPS
Contained glycoepitopes: IEDB_136906,IEDB_137340,IEDB_137472,IEDB_141794,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_151528,IEDB_151531,IEDB_190606,IEDB_232584,IEDB_983931,SB_192,SB_7
Methods: 1H NMR, methylation, mild acid hydrolysis, Smith degradation
Biosynthesis and genetic data: genetic data
Related record ID(s): 113359
NCBI Taxonomy refs (TaxIDs): 623,
562Reference(s) to other database(s): GTC:G01599CO, CCSD:
833, CBank-STR:10766
Show glycosyltransferases
There is only one chemically distinct structure: