Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
Publication DOI: 10.1016/S0008-6215(00)88068-4Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Division of Biochemistry and Biophysics, Bureau of Biologies, Food and Drug Administration, 8800 Rockville Pike, Bethesda, Maryland 20205 U.S.A.
The structure of the Escherichia coli K7 capsular polysaccharide has been investigated by a combination of chemical and spectroscopic methods. The structure of the repeating unit of the polymer was found to be →3)-β-d-ManNAcA-(1→4)-β-d-Glc-(1→; the O-6 atom of the d-glucosyl residue in the repeating unit is acetylated. The K7 polysaccharide is cross-reactive with the Streptococcus pneumoniae type 3 polysaccharide, the structure of which had previously been determined; our n.m.r. studies of the S. pneumoniae type 3 polysaccharide are in accord with this structure. The E. coli K7 and K56 capsular antigens have been shown by serology and 13C-n.m.r. spectroscopy to be identical.
Structure type: polymer chemical repeating unit
Location inside paper: 1
Compound class: CPS
Contained glycoepitopes: IEDB_142488,IEDB_146664,IEDB_983931,SB_192
Related record ID(s): 101034, 113677
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G88091MC, GlycomeDB:
657
Show glycosyltransferases
There is only one chemically distinct structure: