Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperNCBI PubMed ID: 2853000Publication DOI: 10.1016/0008-6215(88)80050-8Journal NLM ID: 0043535Publisher: Elsevier
Institutions: Department of Chemistry, University of British Columbia, Vancouver, B.C., V6T 1Y6 Canada
The structure of the capsular polysaccharide from Escherichia coli O8:K44 (A):H− (K44 antigen) has been established using the techniques of methylation, β-elimination, deamination, and Smith degradation. N.m.r. spectroscopy (13C and 1H) was used extensively to establish the nature of the anomeric linkages of the polysaccharide and of oligosaccharides derived through degradative procedures. The K antigen is comprised of repeating units of the linear tetrasaccharide shown. This acidic polysaccharide represents the first instance of an E. coli K antigen in this series (group A) that has been found to contain two different 2-acetamido-2-deoxyhexoses [formula; see text].
Structure type: polymer chemical repeating unit
Location inside paper: abstract, table II
Compound class: K-antigen
Contained glycoepitopes: IEDB_115136,IEDB_130648,IEDB_136105,IEDB_137340,IEDB_137473,IEDB_140630,IEDB_141807,IEDB_151531,IEDB_225177,IEDB_423153,IEDB_885823
Methods: 13C NMR, 1H NMR, methylation, periodate oxidation, sugar analysis, GLC, b-elimination, Smith degradation, paper chromatography, deamination, ion-exchange chromatography, oxidation with chromium trioxide, reduction
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G32234WJ, GlycomeDB:
5761
Show glycosyltransferases
1H NMR data: present in publication
|
13C NMR data: present in publication
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There is only one chemically distinct structure:
Found 
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