Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Campylobacter jejuni [ICD11:
XN4Q5 
]
The structure was elucidated in this paperNCBI PubMed ID: 7544281Journal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: Department of Microbiology, University College, Galway, Ireland, Department of Chemistry, York University, Toronto, Ontario, Canada, Carbohydrate Research Centre, Department of Molecular and Medical Genetics, University of Toronto, Ontario, Canada
The complete structure for the core oligosaccharide region of the water-insoluble low-Mr, lipopolysaccharide of Campylobacter jejuni serotype 0:3 from phenol/water extraction of bacterial cells was assigned through studies on derivatives of the liberated oligosaccharide. Structure determinations were performed using 1H-NMR and 31P-NMR spectroscopies, methylation analysis supported by fast-atom-bombardment mass spectrometry, and Smith degradation experiments. It was concluded that the complete chains in the core oligosaccharide had the following structure in which a proportion of the terminal residues were phosphorylated: . From a similar series of experiments, it was concluded that an associated polysaccharide, which was isolated from the water phase of the phenoVwater extracts, had the following repeating unit in which a proportion of the previously unknown L-glycero-D-ido-heptose (L-a-D-ido-Hep) residues were present as 3-hydroxypropanoyl esters, and were not covalently linked to the lipopolysaccharide: -[ā3)-L-a-D-Ido-Hep-(lā4)-a-D-Gal-(l-]n-.
Lipopolysaccharide, LPS, structure, core, polysaccharide, O-antigen, Campylobacter, Campylobacter jejuni, core region, region
Structure type: oligomer
Location inside paper: Fig. 1, OS 3-3
Compound class: core oligosaccharide
Contained glycoepitopes: IEDB_130648,IEDB_130701,IEDB_136906,IEDB_137472,IEDB_137473,IEDB_141794,IEDB_144983,IEDB_151528,IEDB_152206,IEDB_164174,IEDB_190606,IEDB_983930,SB_197,SB_21,SB_44,SB_67,SB_7,SB_72
Methods: deacetylation, NMR-2D, FAB-MS, GC-MS, dephosphorylation, GC, Smith degradation
Comments, role: product of Smith degradation
Related record ID(s): 49, 106, 115, 117, 118
NCBI Taxonomy refs (TaxIDs): 197
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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