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1. (Article ID: 12078)
 
Chiba M, Hisada S, Nishibe S, Thieme H
13C NMR analysis of symplocosin and (+)-epipinoresinol glucoside
Phytochemistry 19 (1980) 335-336
 

The structures are described of (-)-epipinoresinol-β-D-glucoside (symplocosin) from Symplocos lucida and (+)-epipinoresinol-β-D-glucoside from Forsythia sp.

13C NMR, Oleaceae, lignans, Symplocos lucida, Symplocaceae, Forsythia species, epipinoresinol-β-D-glucoside

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2. (Article ID: 12525)
 
Nikaido T, Ohmoto T, Kinoshita T, Sankawa U, Nishibe S, Hisada S
Inhibition of cyclic AMP phosphodiesterase by lignans
Chemical and Pharmaceutical Bulletin 29(12) (1981) 3586-3592
 

Cyclic adenosine monophosphate (AMP) phosphodiesterase inhibitors contained in Forsythia suspensa were identified as lignans, (+)-pinoresinol (Ia) and (+)-pinoresinol-β-D-glucoside (Id), and their structure-activity relationship was investigated. In pinoresinol congeners, the configuration of the two phenyl rings is very important in relation to the activity. When both of the p-hydroxyl groups in matairesinol congeners are substituted by methyl or glucose, the activities are decreased as compared with those of the unsubstituted compounds.

inhibitors, Forsythia suspensa, lignans, cAMP phosphodiesterase, (+)-pinoresinol, (+)-pinoresinol-β-D-glucoside, (-)-matairesinol

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