Taxonomic group: bacteria / Firmicutes
(Phylum: Firmicutes)
Associated disease: infection due to Streptococcus pneumoniae [ICD11:
XN3PW 
]
NCBI PubMed ID: 14670720Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: s.oscarson
organ.su.se
Institutions: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden
Two tetrasaccharides, α-D-GlcAp-(1→3)-α-D-Galp-(1→3)-β-D-ManpNAc-(1→4)-β-D-G lcp and α-D-GlcAp-(1→3)-α-D-Glcp-(1→3)-β-D-ManpNAc-(1→4)-β-D-Glcp (protected form), and a pentasaccharide, α-D-Glcp-(1→4)-α-D-GlcAp-(1→3)-α-D-Galp-(1→3)-β-D-ManpNAc-(1→4)-β-D-Glcp have been synthesised from 2-aminoethyl glycoside trisaccharide acceptors in a linear approach via consecutive α-glycosylations. Ethyl thioglycosides were used as glycosyl donors and DMTST in Et(2)O or NIS/TfOH in CH(2)Cl(2) were employed as promoters
glycoconjugate vaccines, oligosaccharide synthesis, Thioglycosides
Structure type: oligomer
Location inside paper: Fig. 3
Contained glycoepitopes: IEDB_115136,IEDB_120354,IEDB_136906,IEDB_137472,IEDB_140630,IEDB_141794,IEDB_142488,IEDB_146664,IEDB_151528,IEDB_190606,IEDB_885813,IEDB_983931,SB_192,SB_7
Methods: NMR, MALDI-TOF MS
Synthetic data: chemical
Comments, role: fragment of capsular polysaccharide
Related record ID(s): 26, 123
NCBI Taxonomy refs (TaxIDs): 1313
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error