Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperNCBI PubMed ID: 6202518Publication DOI: 10.1111/j.1432-1033.1984.tb08137.xJournal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: Max-Planck-Institut für Immunbiologie, Stübeweg 51, D-7800 Freiburg-Zähringen, Federal Republic of Germany
The chemical structure of the outer (hexose) regions of the core oligosaccharide from Escherichia coli 09 with the complete R1 core, and from a R1-derived rfe mutant were analyzed using compositional analysis, methylation and gas chromatography/mass spectrometry. It was found that, in contrast to the branched outer region of the R1 core, the outer region of the core from the rfe mutant lacked terminal glucose and was linear. These results are in agreement with recent findings on the biosynthesis of the 09 antigen. They suggest a cotransfer of glucose with the 09-specific mannan to a 'pre-core' lacking terminal glucose, as the assembly (translocation) step in the 09 antigen synthesis. Thus it is suggested that the initiation of O-chain synthesis (by the formation of an acceptor glucolipid ) and the termination of core synthesis are closely correlated. In conjunction with previous biochemical data, the analytical results presented here indicate a novel core synthesis.
Structure type: oligomer
Aglycon: (->3) Hep+Kdo+Lipid A
Compound class: O-polysaccharide, O-antigen, LPS
Contained glycoepitopes: IEDB_131186,IEDB_135818,IEDB_136906,IEDB_137472,IEDB_141794,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_151528,IEDB_153543,IEDB_190606,IEDB_983931,SB_192,SB_7
Methods: GC-MS
Comments, role: terminal b-Glc carries mannan at unknown position
Related record ID(s): 122529
NCBI Taxonomy refs (TaxIDs): 1010797Reference(s) to other database(s): GTC:G68489YV, GlycomeDB:
26361
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error