Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
];
infection due to Proteus mirabilis [ICD11:
XN9ZF ]
The structure was elucidated in this paperNCBI PubMed ID: 6548705Publication DOI: 10.1111/j.1432-1033.1984.tb08543.xJournal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: Forschungsinstitut Borstel, Institut für Experimentelle Medizin und Biologie, Borstel
After mild acid hydrolysis, a disaccharide of 3-deoxy-D-manno-octulosonic acid (dOclA) was obtained from Re-mutant lipopolysaccharide of Salmonella minnesota, Salmonella godesberg, Proteus mirabilis, and Escherichia coli, and from the lipopolysaccharide of an S. minnesota Rb2 mutant. Combined gas-liquid chromatography/mass spectrometry of the reduced and permethylated derivatives indicated that the disaccharide is interlinked by a 2→4-glycosidic bond in all lipopolysaccharides tested. In addition, it was shown by gas-liquid chromatography of appropriate synthetic standards and a previously characterized α2→4-linked dOclA disaccharide (derived from lipopolysaccharide of S. godesberg) that the non-reducing dOclA residue possesses the alpha configuration. In the case of lipopolysaccharide of S. minnesota Rb2 mutant, this result, together with earlier findings, suggests that it contains a linear dOclA trisaccharide of the sequence dOclA(α2-4)dOclA. The results show that a dOclA(α2-4)dOclA disaccharide represents a common architectural principle in enterobacterial lipopolysaccharides.
Structure type: oligomer
Location inside paper: Re
Aglycon: lipid A
Trivial name: outer core region
Compound class: core oligosaccharide, LOS, LPS
Contained glycoepitopes: IEDB_130650,IEDB_130659,IEDB_2189047
Methods: GC-MS
Related record ID(s): 1785, 7159, 23400, 24248, 24941, 122851, 122853
NCBI Taxonomy refs (TaxIDs): 562,
584,
590,
70803Reference(s) to other database(s): GTC:G38337UV, GlycomeDB:
16228
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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