Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: (Actinopterygii)
Associated disease: hemorrhagic septicemia [ICD11:
MA15.Y 
];
vibriosis [ICD11:
XN8RL ]
NCBI PubMed ID: 2920731Journal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: Department of Fisheries and Oceans, Experimental Sciences Division, St. John's, Newfoundland, Canada
Conjugation of simple ketoses (such as 3-deoxy-D-manno-2-octulosonic acid and N-acetylneuraminic acid) and of various O-specific polysaccharides (from Aeromonas hydrophila and Aeromonas salmonicida) to the bifunctional spacer 1,6-hexanediamine, was achieved by reductive amination. The saccharide--1-(6-amino)-hexane alkyamines obtained were converted into the corresponding isothiocyanate derivatives and coupled to the free epsilon-amino group of lysine residues of the protein carrier bovine serum albumin. In similar manner, the aldehyde group introduced by selective periodate oxidation into the partially O-deacylated lipopolysaccharide of Vibrio anguillarum was conjugated to 1,6-hexanediamine, converted into the corresponding isothiocyanate and covalently attached to bovine serum albumin.
Structure type: polymer chemical repeating unit ; n=10
Aglycon: core, C3 of Rha
Compound class: O-polysaccharide, O-antigen
Methods: 13C NMR
Comments, role: O-antigen of the lipopolysaccharide, terminated with 4-linked bLQuip3NAc4Me, linked at position 3 of rhamnose of the core
Related record ID(s): 123255, 123257
NCBI Taxonomy refs (TaxIDs): 55601
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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