Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Citrobacter [ICD11:
XN0FZ 
]
The structure was elucidated in this paperNCBI PubMed ID: 7744044Publication DOI: 10.1111/j.1432-1033.1995.0299l.xJournal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: Max-Planck-Institut fur Medizinische Forschung, Heidelberg, Germany
Sugar analysis of the O-specific polysaccharide produced by Citrobacter serotype O41 revealed the presence of a hexasaccharide repeating unit, which includes the unusual 3-amino-N-(D-3'-hydroxybutyryl)-3,6-dideoxy-D-galactosyl residue (Fuc3NAcyl). The structure of the repeating unit was determined by extensive use of homo- and heteronuclear two-dimensional NMR spectroscopy, including the application of long-range 1H-13C correlation experiments and NOE studies to establish the sequence of sugar units. Indentification of the Glc β1→2 Fuc3NAcyl β1→6 GlcNAc α1→ sequence at the non-reducing terminus establishes the biological repeating unit of this O-specific polysaccharide as: →2 Glc β1→ Fuc3NAcyl β1→6 GlcNAc α1→ (Glc α1→2) 4Gal β1→3 GalNAc β1→. This structure is similar to that found for the O-specific polysaccharide isolated from Hafnia alvei strain 1211 [Katzenellenbogen, E., Romanowska, E., Dabrowski, U. & Dabrowski, J. (1991) Eur. J. Biochem. 200, 401-407], which differs in having an acetyl substituent at O4 of the Fuc3NAcyl residue and a branch point of GalNAc α substituted by Glc β at O3; these differences are responsible for the only weak serological cross-reactivity of the two strains.
Lipopolysaccharide, 6-dideoxy-D-galactose, endotoxin, Citrobacter, 3-amino-N-(D-3'-hydroxybutyryl)-3
Structure type: polymer chemical repeating unit
Compound class: O-polysaccharide
Contained glycoepitopes: IEDB_130648,IEDB_134627,IEDB_136044,IEDB_137340,IEDB_137472,IEDB_137473,IEDB_141794,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_147450,IEDB_151531,IEDB_153217,IEDB_190606,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_23,SB_24,SB_7,SB_8,SB_88
Methods: 13C NMR, 1H NMR, methylation, periodate oxidation, NMR-2D
Biosynthesis and genetic data: genetic data
Related record ID(s): 4318
NCBI Taxonomy refs (TaxIDs): 544
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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