Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Organ / tissue: cell wall
NCBI PubMed ID: 7828729Journal NLM ID: 0155157Publisher: Elsevier
Institutions: Institute for Molecular Cell Biology, University of Amsterdam, The Netherlands
The Calcofluor white-hypersensitive mutants cwh52 and cwh53 are severely reduced in β-1,3-glucan. CWH52 was equivalent to GAS1. CWH53 represented a new gene, located on the right arm of chromosome XII, and predicted to encode a 215 kDa protein with multiple transmembrane domains. The transcription of CWH53 was cell cycle-dependent and, similar to GAS1/CWH52, increased in late G1, indicating that the formation of β-glucan is cell cycle-regulated. Further, in some mutant alleles of both gas1/cwh52 and cwh53 lethal concentrations of Calcofluor induced growth arrest at a specific phase of the cell cycle.
Structure type: homopolymer ; n is large
Trivial name: β-1,3-glucan, pachyman, curdlan, SSG
Compound class: EPS, glucan, cell wall glucn, cell wall glucan, cell wall glucoprotein
Contained glycoepitopes: IEDB_1397514,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_2278476,IEDB_2278477,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Related record ID(s): 103899, 106266, 110076, 110100, 110138, 111873, 111972, 111976, 118123, 125281, 126051, 130953, 130960, 130963, 139820, 139829, 141508, 149482
NCBI Taxonomy refs (TaxIDs): 4932Reference(s) to other database(s): GTC:G51056AN, GlycomeDB:
157, CCSD:
50422, CBank-STR:4225
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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