Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Organ / tissue: cell wall
NCBI PubMed ID: 7781974Journal NLM ID: 7705721Publisher: Blackwell Publishing
Institutions: Institute of Molecular Cell Biology, University of Amsterdam, The Netherlands
The cell wall of Candida albicans contains mannoproteins that are covalently associated with β-1,6-glucan. When spheroplasts were allowed to regenerate a new cell wall, initially non-glucosylated cell wall proteins accumulated in the medium. While the spheroplasts became osmotically stable, β-1,6-glucosylated proteins could be identified in their cell wall by SDS-extraction or β-1,3-glucanase digestion. At later stages of regeneration, β-1,3-glucosylated proteins were also found. Hence, incorporation of proteins into the cell wall is accompanied by extracellular coupling to β-1,6-/β-1,3-glucan. The SDS-extractable glucosylated proteins probably represent degradation products of wall proteins rather than their precursors. Tunicamycin delayed, but did not prevent the formation of β-1,6-glucosylated proteins, demonstrating that β-1,6-glucan is not attached to N-glycosidic side-chains of wall proteins.
Structure type: homopolymer ; n is large
Trivial name: β-1,3-glucan, pachyman, curdlan, SSG
Compound class: EPS, glucan, cell wall glucn, cell wall glucan, cell wall glucoprotein
Contained glycoepitopes: IEDB_1397514,IEDB_142488,IEDB_146664,IEDB_153543,IEDB_158555,IEDB_161166,IEDB_2278476,IEDB_2278477,IEDB_558869,IEDB_857743,IEDB_983931,SB_192
Related record ID(s): 20152, 103899, 106266, 110076, 110100, 110138, 111873, 111972, 111976, 112990, 118123, 125281, 125854, 126052, 130953, 130960, 130963, 139820, 139829, 141508, 149482
NCBI Taxonomy refs (TaxIDs): 5476Reference(s) to other database(s): GTC:G51056AN, GlycomeDB:
157, CCSD:
50422, CBank-STR:4225
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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