Taxonomic group: fungi / Ascomycota
(Phylum: Ascomycota)
Organ / tissue: cell wall
NCBI PubMed ID: 7781974Journal NLM ID: 7705721Publisher: Blackwell Publishing
Institutions: Institute of Molecular Cell Biology, University of Amsterdam, The Netherlands
The cell wall of Candida albicans contains mannoproteins that are covalently associated with β-1,6-glucan. When spheroplasts were allowed to regenerate a new cell wall, initially non-glucosylated cell wall proteins accumulated in the medium. While the spheroplasts became osmotically stable, β-1,6-glucosylated proteins could be identified in their cell wall by SDS-extraction or β-1,3-glucanase digestion. At later stages of regeneration, β-1,3-glucosylated proteins were also found. Hence, incorporation of proteins into the cell wall is accompanied by extracellular coupling to β-1,6-/β-1,3-glucan. The SDS-extractable glucosylated proteins probably represent degradation products of wall proteins rather than their precursors. Tunicamycin delayed, but did not prevent the formation of β-1,6-glucosylated proteins, demonstrating that β-1,6-glucan is not attached to N-glycosidic side-chains of wall proteins.
Structure type: homopolymer ; n is large
Trivial name: pustulan, β-1,6-glucan
Compound class: cell wall glucoprotein
Contained glycoepitopes: IEDB_135614,IEDB_141806,IEDB_142488,IEDB_146664,IEDB_241101,IEDB_983931,SB_192
Related record ID(s): 124916, 125818, 126051
NCBI Taxonomy refs (TaxIDs): 5476Reference(s) to other database(s): GTC:G26777BZ, CCSD:
46952, CBank-STR:4234
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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