Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
The structure was elucidated in this paperJournal NLM ID: 8705043Publisher: M.B.R. Press
Institutions: Department of Biological Chemistry, Indian Association for the Cultivation of Sciences, Calcutta, India
The O-specific polysaccharide isolated from the non-capsulated Escherichia coli O125: K-:H19 lipopolysaccharide contains L-fucose, D-mannose, D-galactose, D-glucos and 2-acetamido-2-deoxy-D-galactose in the molar retios 1:1:1:1:1.7. The primary structure of the O-specific polysaccharide was established by compositional analysis, methylation studies, enzymatic hydrolysis and with the 1H and 13C NMR spectroscopy. These studies revealed that the O-antigen is branched and built up of repeating hexasaccharide unit having th following structure: (see struc. in text). This structure is similar to that of recently reported during the course of our investigation for the O-antigenic polysaccharide for a capsulated strain of Escherichia coli O125:K72:H19 of European origin.
Lipopolysaccharide, structure, chain, side chain, Escherichia, Escherichia coli, O-specific
Structure type: suggested polymer biological repeating unit
Location inside paper: abstract
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_130648,IEDB_130701,IEDB_134627,IEDB_136044,IEDB_136045,IEDB_137472,IEDB_137473,IEDB_1391961,IEDB_141584,IEDB_141794,IEDB_142488,IEDB_142489,IEDB_144562,IEDB_144983,IEDB_144998,IEDB_146664,IEDB_147450,IEDB_152206,IEDB_152214,IEDB_174333,IEDB_190606,IEDB_885822,IEDB_983930,IEDB_983931,SB_165,SB_166,SB_187,SB_192,SB_195,SB_23,SB_24,SB_44,SB_67,SB_7,SB_72,SB_8,SB_86,SB_88
Methods: 13C NMR, 1H NMR, methylation, sugar analysis, enzymatic hydrolysis, Smith degradation
Enzymes that release or process the structure: α-L-fucosidase, α-D-glucopyranosidase or β-D-galactopyranosidase
Comments, role: biological repeat frame was based on GT homology analysis; chemical repeat frame is different in the paper
Related record ID(s): 893, 1349, 20678
NCBI Taxonomy refs (TaxIDs): 562Reference(s) to other database(s): GTC:G41918HP, GlycomeDB:
25322
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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