Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: (Actinopterygii); Cyprinus carpio
Associated disease: motile aeromonad septicemia (MAS)
NCBI PubMed ID: 9245137Publication DOI: 10.1016/j.carres.2017.11.010Journal NLM ID: 0043535Publisher: Elsevier
Correspondence: zonggh
cau.edu.cn; zhangjianjun
cau.edu.cn
Institutions: Department of Applied Chemistry, China Agricultural University, Beijing, PR China
Aeromonas bestiarum 207 is a bacterial pathogen with severe impact on aquaculture. In a recent study, the structure of OPS antigens from Aeromonas bestiarum was identified as pentasaccharide repeating units. Synthesis of the pentasaccharide repeating unit and its derivative are reported. Stereo- and regio-specific synthesis was achieved under Schmidt glycosylation conditions employing appropriately protected L-rhamopyranosyl and D-glucopyranosylamine building blocks. The pentasaccharide synthesis was achieved using a [3 + 2] strategy with an overall yield of 5.2% through 11 linear steps from the monosaccharide building blocks 10 and 14.
O-specific polysaccharide, Aeromonas bestiarum, Aquaculture, Carbohydrate pesticide, Pentasaccharide synthesis
Structure type: polymer chemical repeating unit
Location inside paper: p.11, scheme 1
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_133754,IEDB_135813,IEDB_136105,IEDB_137340,IEDB_141807,IEDB_143253,IEDB_144825,IEDB_151531,IEDB_225177,IEDB_885823
Methods: 13C NMR, 1H NMR, TLC, ESI-MS, chemical synthesis, chemical methods, glycosylation, optical rotation measurement
Related record ID(s): 12830
NCBI Taxonomy refs (TaxIDs): 105751Reference(s) to other database(s): GTC:G84110KK, GlycomeDB:
34700
Show glycosyltransferases
There is only one chemically distinct structure:
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