Taxonomic group: bacteria / Firmicutes
(Phylum: Firmicutes) Associated disease: infection due to Bacillus subtilis [ICD11:
XM4SG9 ]
NCBI PubMed ID: 8294463 Journal NLM ID: 2985121R Publisher: Baltimore, MD: American Society for Biochemistry and Molecular Biology
Institutions: Northwest Center for Medical Education, Indiana University School of Medicine, Gary 46408
The same 70-kDa protein, present on the surface of mouse lymphocytes, served as the predominant binding site for heparin, heparinoids, and bacterial lipoteichoic acids, as well as peptidoglycan and lipopolysaccharides. This conclusion was supported by the following results: (a) all of these compounds photoaffinity cross-linked to one major 70-kDa 6.5-7.0 pI protein that co-migrated on two-dimensional polyacrylamide gel electrophoresis; (b) peptide maps of the 70-kDa proteins digested with chymotrypsin, subtilisin, protease V, or papain yielded the same peptides for heparin-, lipoteichoic acid-, peptidoglycan-, and lipopolysaccharide-binding proteins; (c) cross-linking of peptidoglycan, lipopolysaccharide, lipoteichoic acid, and heparin was competitively inhibited by the same compounds with the same order of potency, i.e. carboxyl-reduced sulfated heparin > peptidoglycan > pentosan polysulfate > heparin > chitin > dextran sulfate > trestatin sulfate > polyanetholesulfonate > fucoidan > beta-cyclodextrin tetradecasulfate > heparan sulfate > carrageenan lambda > lipoteichoic acids > Re-lipopolysaccharide > lipopolysaccharide > lipid A > polygalacturonic acid; and (d) cross-linking of each of these ligands was not inhibited by carboxyl-reduced heparin, dextran, beta-cyclodextrin, trestatin, carrageenan kappa, chondroitin 4-sulfate, chondroitin 6-sulfate, beta-D-glucan, carboxy-methylcellulose, levan, alpha-D-mannan, and glycogen. The minimum size of the molecule that bound was 7-9 glycan residues, whereas, di- and trisaccharides did not bind. There was a logarithmic linear relationship between the strength of the binding and the length of the polymer (up to > 1500 glycan residues), which indicates an avidity effect of the cooperative binding of one polymeric molecule to several receptor molecules on the cell surface. The 70-kDa receptor, therefore, has a broad, but limited specificity of binding for non-charged (peptidoglycan and chitin), highly negatively charged (heparin and heparinoids), and weakly negatively charged (lipoteichoic acids, lipopolysaccharides, and lipid A) ligands.
Structure type: oligomer
Location inside paper: LTA B.s.
Compound class: lipoteichoic acid
Contained glycoepitopes: IEDB_137340,IEDB_141806,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_146664,IEDB_151531,IEDB_241101,IEDB_241118,IEDB_983931,SB_192
Comments, role: LIP = acyl C14-C19
Related record ID(s): 136955, 136956, 136957, 136960, 136961, 136962, 136963, 136965, 136967, 236963
NCBI Taxonomy refs (TaxIDs): 1423
Show glycosyltransferases
There are too many chemically distinct structures (729) corresponding to the specified structure with alternative fragments (<..>), so only one was processed further:
xDAla?(?-2)[xDAla?(?-2)[xDAla?(?-2)[xDAla?(?-2)[xDAla?(?-2)[xDAla?(?-2)[xDGro(3-P-1)]xDGro(3-P-1)]xDGro(3-P-1)]xDGro(3-P-1)]xDGro(3-P-1)]xDGro(3-P-1)]xDGro(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro There are 64 chemically distinct structures for the variant above. Please, select:
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(1-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(1-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDAla?(2-2)[xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-1)]xDGro?(3-P-6)bDGlcp(1-6)bDGlcp(1-1)[LIP(1-3),LIP(1-2)]x?Gro?
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