Taxonomic group: bacteria / Firmicutes
(Phylum: Firmicutes)
Associated disease: infection due to Streptococcus pneumoniae [ICD11:
XN3PW 
]
The structure was elucidated in this paperNCBI PubMed ID: 9432005Publication DOI: 10.1111/j.1432-1033.1997.00163.xJournal NLM ID: 0107600Publisher: Oxford, UK: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies
Institutions: Institute for Biological Sciences, National Research Council of Canada, Ottawa ON
The specific polysaccharide antigen of Streptococcus pneumoniae serotype 35A was shown, by a combination of one- and two-dimensional NMR methods and chemical analyses, to be a high-molecular-mass polymer composed of D-galactose, D-glucose, mannitol, and phosphate (3:1:1:1). The pentasaccharide repeating unit is polymerized through phosphate diester linkages to give the structure, [formula in text] O-Acetyl substituents are present at positions 5 and 6 of the 3)-β-D-Galf residue and at position 2 of the 6)-β-D-Galf residue. The capsular polysaccharides of S. pneumoniae serotypes 20 and 35A both contain the disaccharide unit →3)-β-D-Galf-(1→3)-β-D-Glcp-(1→ which is the probable structural determinant responsible for the serological cross reactivity of the two polysaccharides
structure, Streptococcus pneumoniae, antigenic determinant, capsular polysaccharides
Structure type: polymer chemical repeating unit
Location inside paper: p. 167, S. pneumoniae 20 CPS
Compound class: CPS
Contained glycoepitopes: IEDB_136095,IEDB_137340,IEDB_137472,IEDB_141807,IEDB_142488,IEDB_144998,IEDB_144999,IEDB_146664,IEDB_150077,IEDB_151531,IEDB_190606,IEDB_241118,IEDB_983931,SB_192
Methods: FAB-MS, GC-MS, GC-EI-MS, NMR, HF solvolysis, de-O-acylation
Related record ID(s): 1611, 1927, 6412, 112075
NCBI Taxonomy refs (TaxIDs): 1313Reference(s) to other database(s): GTC:G35314XD, GlycomeDB:
16877
Show glycosyltransferases
There is only one chemically distinct structure: