In the present study, the species: Beauveria bassiana, Absidia coerulea and Absidia glauca were used in biotransformation of flavones (chrysin, apigenin, luteolin, diosmetin) and flavanones (pinocembrin, naringenin, eriodictyol, hesperetin). The Beauveria bassiana AM 278 strain catalyzed the methylglucose attachment reactions to the flavonoid molecule at positions C7 and C3'. The application of the Absidia genus (A. coerulea AM 93, A. glauca AM 177) as the biocatalyst resulted in the formation of glucosides with a sugar molecule present at C7 and C3' positions of flavonoids skeleton. Nine of obtained products have not been previously reported in the literature.
biotransformation, Beauveria bassiana, Absidia coerulea, microbial glycosylation, Absidia glauca, flavanones, flavones
NCBI PubMed ID: 30755333Publication DOI: 10.1016/j.bioorg.2019.01.046Journal NLM ID: 1303703Publisher: Orlando, FL: Academic Press
Correspondence: Sordon S
; Popłoński J ; Tronina T ; Huszcza E
Institutions: Department of Chemistry, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, HPLC, biosynthetic methods, extraction, cell growth, HR-ESI-MS
Found