Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: infection due to Burkholderia pseudomallei [ICD11:
XN3LD 
];
infection due to Pseudomonas pseudomallei [ICD11:
XN8AA ]
Publication DOI: 10.1080/07328300802030761Journal NLM ID: 8218151Publisher: Marcel Dekker
Correspondence: parthasarathy
us.army.mil
Institutions: Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, MD, USA
Burkholderia pseudomallei is the causative agent of melioidosis, a bacterial infection endemic in tropical regions including southeast Asia and northern Australia. B. pseudomallei contains structurally unique polysaccharides (capsular polysaccharide and O 2 antigen saccharides of lipopolysaccharide). A polysaccharide microarray platform was developed by immobilizing these polysaccharides onto glass slides. Employing this microarray, we were able to demonstrate the presence of antibodies to these polysaccharide antigens in the sera of melioidosis patients, but not in serum from nonmelioidosis human subjects. The advantages of this polysaccharide microarray technology over the conventional tests for the serodiagnosis of melioidosis are discussed.
Burkholderia pseudomallei, melioidosis, polysaccharide microarray, serodiagnosis
Structure type: homopolymer
Location inside paper: p.35, type B
Trivial name: 6-deoxy-heptan CPS
Compound class: CPS, O-polysaccharide, O-antigen
Methods: serological methods
Biological activity: serological data
Related record ID(s): 2467, 4040, 6576, 6577, 7121, 10328, 23409, 23437, 108414, 116824
NCBI Taxonomy refs (TaxIDs): 28450Reference(s) to other database(s): GTC:G09650IH, GlycomeDB:
3383
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
report error
(previously named: Pseudomonas pseudomallei)