CSDB: Search results

Taxonomic group: bacteria / Proteobacteria (Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: bronchitis [ICD11: CA20

, ICD11: CA20.Z

]; infection due to Pseudomonas aeruginosa [ICD11: XN5L6

]

NCBI PubMed ID: 19000720
Journal NLM ID: 8306883
Correspondence: Eleonora.altman

nrc-cnrc.gc.ca (E. Altman)
Institutions: Institute for Biological Sciences, National Research Council of Canada, 100 Sussex Drive, Ottawa, Ontario, Canada K1A 0R6

The aim of the present investigation was to develop a novel approach for rapid identification and differentiation of Pseudomonas aeruginosa clones from Canadian cystic fibrosis patients by capillary electrophoresis-mass spectrometry. We screened P. aeruginosa isolates for lipopolysaccharide structure and presence/absence of alginate and correlated these findings with antibiotic resistance patterns.

Lipopolysaccharide, structure, Pseudomonas aeruginosa, mass spectrometry, cystic fibrosis, drug resistance

Structure type: polymer chemical repeating unit
Location inside paper: p. 205, fig.2B
Compound class: O-polysaccharide, O-antigen
Contained glycoepitopes: IEDB_136105,IEDB_225177,IEDB_885823

Methods: serological methods, CE-MS
Biological activity: serological data
Comments, role: Pseudomonas aeruginosa clonal strain A; published polymerization frame was shifted for conformity with other records.

Related record ID(s): 23646, 23959, 24047
NCBI Taxonomy refs (TaxIDs): 287
Reference(s) to other database(s): GTC:G61195BH, GlycomeDB:33497
Show glycosyltransferases

There is only one chemically distinct structure:

*O[C@H]1[C@@H](C(N)=O)O[C@H](O[C@H]2[C@@H](C(=O)O)O[C@H](O[C@H]3[C@H](O)[C@@H](C)O[C@H](O[C@H]4[C@@H](O)[C@H](*)O[C@@H](C)[C@@H]4O)[C@@H]3NC(C)=O)[C@H](NC=O)[C@H]2O)[C@H](NC(C)=O)[C@H]1O

SVG MW SMILES 3D mol Ionize