Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Campylobacter jejuni [ICD11:
XN4Q5 
]
The structure was elucidated in this paperNCBI PubMed ID: 19422007Publication DOI: 10.1002/cbic.200900018Journal NLM ID: 100937360Publisher: Weinheim, Germany: Wiley Interscience
Correspondence: mtanner
chem.ubc.ca
Institutions: Department of Chemistry, The University of British Columbia, 2036 Main Mall, Vancouver, B.C. V6T 1Z1, Canada, Institute for Biological Sciences, National Research Council Ottawa, Ontario K1A 0R6 Canada
Catch a tiger by the tail: We have demonstrated that by feeding nonmotile mutant C. jejuni bacteria with a neutral azide-labelled pseudaminic acid precursor we can restore their ability to generate functional flagella. The presence of azido-pseudaminic acid on the surface of the flagella provides a bio-orthogonal chemical handle that can be used to modify the flagellar proteins.
metabolism, Campylobacter jejuni, engineering, flagella, azides, C. jejuni, Staudinger reaction, cell surfaces
Structure type: monomer
Location inside paper: p.1317, scheme 1,1
Trivial name: UDP-6-deoxy-AltNAc4NAcCl
Methods: 1H NMR, SDS-PAGE, chemical methods, MS, biochemical methods
Biological activity: motility data
Synthetic data: chemoenzymatic
Comments, role: in vitro Az-Pse synthesis
Related record ID(s): 23771, 24082, 24084, 24085, 24086
NCBI Taxonomy refs (TaxIDs): 354242
Show glycosyltransferases
There is only one chemically distinct structure:
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(later renamed to: Campylobacter jejuni subsp. jejuni 81-176)