Taxonomic group: bacteria / Firmicutes
(Phylum: Firmicutes)
Associated disease: infection due to Bacillus subtilis [ICD11:
XM4SG9 
]
The structure was elucidated in this paperNCBI PubMed ID: 19961419Publication DOI: 10.1134/S0006297909120116Journal NLM ID: 0370623Publisher: American Chemical Society
Correspondence: potekchina
hotbox.ru
Institutions: Faculty of Biology, Lomonosov Moscow State University, Moscow, Russia
Cell walls of Bacillus subtilis VKM B-760 and VKM B-764 are characterized by heterogeneous composition of teichoic acids. Polymer I with structure -6)-β-D-Galp-(1→1)-sn-Gro-(3-P-, polymer II with structure -6)-α-D-Glcp-(1→1)-sn-Gro-(3-P-, and a small amount of unsubstituted 1,3-poly(glycerol phosphate) were detected in strain VKM B-760. Strain VKM B-764 contains an analogous set of teichoic acids, but a characteristic feature of polymer II is the presence of disubstituted glycerol residue with α-glucopyranose localization in the integral chain at C-1 hydroxyl and β-glucopyranose as a side branch at C-2 hydroxyl (polymer III): -6)-α-D-Glcp-(1→1)-[β-D-Glcp-(1→2)]-sn-Gro-(3-P-. The structures of polymer I in bacilli and polymer III in Gram-positive bacteria are described for the first time. Teichoic acids were studied by chemical methods and on the basis of combined analysis of one-dimensional 1H-, 13C-, and (31)P-NMR spectra, homonuclear two-dimensional (1)H/(1)H COSY, TOCSY, and ROESY, and heteronuclear two-dimensional (1)H/(13)C gHSQC- and HMQC-TOCSY experiments. Simultaneous presence of several different structure teichoic acids in the bacillus cell walls as well as chemotaxonomical perspectives of the application of these polymers as species-specific markers for members of the Bacillus genus is discussed.
NMR spectroscopy, cell wall, teichoic acids, Bacillus subtilis
Structure type: polymer chemical repeating unit
Location inside paper: abstract, p.1371
Trivial name: poly(glycosyl 1-phosphate)
Compound class: cell wall polysaccharide, teichoic acid
Methods: 13C NMR, 1H NMR, NMR-2D, HF solvolysis, sugar analysis, 31P NMR, NMR-1D, genetic methods, acid degradation
Biosynthesis and genetic data: genetic data
Related record ID(s): 23819, 24184, 24185, 24186, 24188
NCBI Taxonomy refs (TaxIDs): 1423Reference(s) to other database(s): GTC:G09659CF
Show glycosyltransferases
There is only one chemically distinct structure:
*OCC(O)COP(*)(=O)O
154.058 g/mol (C3H7R2O5P, R = next and previous repeats, not counted in mol weight)
Found 
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