Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Burkholderia pseudomallei [ICD11:
XN3LD 
];
infection due to Pseudomonas pseudomallei [ICD11:
XN8AA ]
The structure was elucidated in this paperNCBI PubMed ID: 11356562Journal NLM ID: 8902526Publisher: Oxford University Press
Correspondence: kawahara-k
kitasato.or.jp
Institutions: Department of Bacteriology, The Kitasato Institute, 5-9-1, Shirokane, Minato-ku, Tokyo 108-8642, Japan, Department of Microbiology, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi-machi, Tochigi 329-0498, Japan, National Institute of Health, Nonthaburi 11000, Thailand, Department of Microbiology, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu 500-8705, Japan
Smooth-type lipopolysaccharide (LPS) of Burkholderia pseudomallei has been reported to contain two kinds of O-antigenic polysaccharides, a 1,3-linked homopolymer of 6-deoxy-heptose and a polymer with a repeating unit of →3)-glucose-(1→3)-6-deoxytalose-(1→ with O-acetyl or O-methyl modifications. A LPS preparation containing these two polysaccharides was separated by gelpermeation chromatography in this study. Chemical analysis of the separated fractions revealed the 6-deoxy-heptane to be a polysaccharide without a lipid portion and the polymer of glucose and 6-deoxy-talose to be an O-antigenic polysaccharide of the LPS. This result was further supported by the assay of these polysaccharide molecules for macrophage activation activity. The 6-deoxy-heptane showed no macrophage activation, indicating that this polysaccharide was not the LPS, but one of the capsular polysaccharides of B. pseudomallei.
Lipopolysaccharide, structure, Burkholderia, Burkholderia pseudomallei, chemical, isolation, preparation, separation, melioidosis
Structure type: homopolymer
Location inside paper: Type-I polysaccharide
Trivial name: 6-deoxy-heptan CPS
Compound class: CPS, O-polysaccharide, O-antigen
Methods: SDS-PAGE, GLC, GPC
Biological activity: macrophage activity data
Related record ID(s): 2529, 2577, 4040, 6576, 6577, 7121, 10328, 23409, 23539, 108414, 116824
NCBI Taxonomy refs (TaxIDs): 28450Reference(s) to other database(s): GTC:G09650IH, GlycomeDB:
3383
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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(previously named: Pseudomonas pseudomallei 3P-62 (GIFU 12046))