Knirel YA, Kochetkov NK The structure of lipopolysaccharides of gram-negative bacteria. II. The structure of the core region Biochemistry (Moscow)58(2) (1993)
84-99
Journal NLM ID:0376536 Publisher: Nauka/Interperiodica Institutions: N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow (Russian Federation)
This review summarizes data on the structure of the core of bacterial lipopolysaccharides (LPS), an oligosaccharide which binds the lipid moiety of LPS to the O-antigenic polysaccharide chain. Both S-strains with complete LPS and R-mutants having various defects of core biosynthesis are considered. The role of the core in the functioning of the outer membrane and in the manifestation of antigenic specificity of LPS is discussed.