Taxonomic group: bacteria / Chlamydiae
(Phylum: Chlamydiae)
Associated disease: infection due to Chlamydia trachomatis [ICD11:
XN4Q4 
]
NCBI PubMed ID: 19900730Journal NLM ID: 7906240Institutions: Division of Medical and Biochemical Microbiology, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
The inner core of lipopolysaccharide (LPS) structures in Gram-negative bacteria is considered a highly conserved region. The sugar connecting the membrane-associated lipid A moiety with the hydrophilic saccharide moiety, 3-deoxy-α-D-manno-oct-2-ulosonic acid (Kdo) is present in every LPS molecule investigated but it may be partially replaced by d-glycero-α-D-talo-oct-2-ulosonic acid (Ko). l-Glycero-α-D-manno-heptose (Hep) and phosphate residues are part of most but not all LPS structures and additionally, modifications with 4-amino-4-deoxy-β-L-arabinose (Ara4N) residues occur in some. A number of different glycosyltransferases is involved in the biosynthesis of the inner core region of different lipopolysaccharides. Here, we report the characterization of Kdo transferases, heptosyltransferases and Ara4N transferases from a variety of bacteria
Lipopolysaccharide, glycosyltransferases
Structure type: oligomer
Location inside paper: p.7, fig.6
Trivial name: core-lipid A
Compound class: LPS
Contained glycoepitopes: IEDB_130650,IEDB_130657,IEDB_130658,IEDB_130659,IEDB_135394,IEDB_135515,IEDB_141807,IEDB_150760,IEDB_150908,IEDB_151531,IEDB_176772,IEDB_534865
Comments, role: major LPS
NCBI Taxonomy refs (TaxIDs): 813
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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