Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Associated disease: infection due to Escherichia coli [ICD11:
XN6P4 
]
NCBI PubMed ID: 19926726Journal NLM ID: 9104124Publisher: IRL Press at Oxford University Press
Correspondence: G. Widmalm <gw
organ.su.se>
Institutions: Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden
ECODAB (the E. coli O-antigen database) has been expanded to include information about glycosyltransferases (GTs) involved in the assembly of the O-antigen polysaccharide. Similarity searches have been performed to be able to determine GT functions that have not been reported prior to this work. In addition to suggesting the function of 179 GTs the approach leads to the prediction of part of the O-antigen structures of a number of serogroups. The procedure suggests a novel way of combining genetic information with experimental techniques in structural analysis of oligo- and polysaccharides.
O-antigen, Escherichia coli, glycosyltransferases, polysaccharides, database
Structure type: oligomer
Location inside paper: p.367, fig.1
Trivial name: repeating O-unit
Contained glycoepitopes: IEDB_130648,IEDB_134627,IEDB_136044,IEDB_136045,IEDB_136906,IEDB_137472,IEDB_137473,IEDB_1391961,IEDB_141584,IEDB_141794,IEDB_142489,IEDB_144562,IEDB_144990,IEDB_147450,IEDB_150767,IEDB_150948,IEDB_151528,IEDB_152214,IEDB_152215,IEDB_153553,IEDB_167071,IEDB_174333,IEDB_190606,IEDB_241096,IEDB_461711,IEDB_461719,IEDB_885822,SB_154,SB_165,SB_166,SB_187,SB_195,SB_23,SB_24,SB_25,SB_7,SB_8,SB_86,SB_88
Methods: genetic methods
Enzymes that release or process the structure: WbsH,WbsK,WbsL,WbsJ
Biosynthesis and genetic data: genetic data, ECODAB(Escherichia coli O-antigen database)
NCBI Taxonomy refs (TaxIDs): 1450177Reference(s) to other database(s): GTC:G14306HI, GlycomeDB:
37813
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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