Taxonomic group: bacteria / Proteobacteria
(Phylum: Proteobacteria)
Host organism: Homo sapiens
Associated disease: hemorrhagic colitis (HC) [ICD11:
1A40.0 
];
hemolytic-uremic syndrome (HUS) [ICD11:
3A21.2 ];
infection due to Escherichia coli [ICD11:
XN6P4 ]
The structure was elucidated in this paperNCBI PubMed ID: 20138327Journal NLM ID: 1303703Publisher: Orlando, FL: Academic Press
Correspondence: akmisra69
gmail.com (A.K. Misra)
Institutions: Division of Molecular Medicine, Bose Institute, A.J.C. Bose Birth Centenary Campus, P-1/12, C.I.T. Scheme VII-M, Kolkata 700 054, India
An expedient total synthesis of a pentasaccharide as its 4-methoxyphenyl glycoside corresponding to the Shiga toxin producing Escherichia coli O171 has been achieved for the first time in excellent yield. Most of the glycosylation steps are highly stereoselective. Stereoselective glycosylation of sialic acid derivative was obtained exploiting the nitrile effect of the solvent used.
Oligosaccharides, sialic acid, pentasaccharide, glycosylation, Escherichia coli O171
Structure type: oligomer
Location inside paper: p.57
Aglycon: 4-methoxyphenyl
Trivial name: repeating unit
Contained glycoepitopes: IEDB_130648,IEDB_134627,IEDB_136044,IEDB_136794,IEDB_137472,IEDB_137473,IEDB_141794,IEDB_142488,IEDB_146100,IEDB_146664,IEDB_147450,IEDB_149174,IEDB_158551,IEDB_190606,IEDB_983931,SB_126,SB_165,SB_166,SB_170,SB_171,SB_172,SB_187,SB_192,SB_195,SB_23,SB_24,SB_7,SB_8,SB_84,SB_88
Methods: 13C NMR, 1H NMR, NMR-2D, TLC, chemical synthesis
Synthetic data: chemical
NCBI Taxonomy refs (TaxIDs): 2100484Reference(s) to other database(s): GTC:G53922OR, GlycomeDB:
37815
Show glycosyltransferases
There is only one chemically distinct structure:
Found 
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